USPlabs: OxyELITE Pro

"It's like Jack3d™ in a pill!"

Continue Reading To Discover The Specific Receptor That May Be Causing Bodyfat To "Automatically" Stick To You Like Crazy - Refusing To Let Go...

The Same Old BS

Since then, stimulant-based "thermogenics" have been all show and no go...

How many caffeine, green tea, synephrine and weak ass "thyroid-boosting" products can be released?

Who do they think they're kidding when the write-up says "We've produced the most unique & effective thermogenic ever!"...

...Umm, no you haven't, it's the same as every other weak burner on the market...

Green Tea For A Six Pack?

Listen, green tea has MANY benefits...It's an awesome antioxidant and is rightfully a staple in many intelligent lifters arsenals...

And, yes, some science suggests it boosts metabolism...but let's be honest, it's not gonna get you ripped...

My grandmother's been drinking it every day for decades and I'm pretty sure she doesn't have a six-pack...

And synephrine...don't even get me started with that...

After establishing Recreate as a top-notch low-stim fat burner, we set out to develop a stim-based fat burner that, well, that supports fat loss!*

...I'm proud to say we've hit paydirt...

Introducing a burner coined the "Super Thermogenic™" by those familiar with its effectiveness...*

It's called OxyELITE Pro™ & It's absolutely unmatched!

Why Is The Last Place To Lose Fat, The First Place To Gain Fat?

It just doesn't seem fair, but unfortunately it's true...

Fat can stick to you like super glue and hang on for dear life...

So why does this happen?

Your BodyFat Held Hostage?

It's called the Alpha-2 receptor - And, if getting ripped is your goal - it can be your absolute worst enemy...

If the Alpha-2 receptor wants you to store fat, you're going to store fat...

The alpha-2 receptor is responsible for inhibiting lipolysis - which basically means it can allow the body to store fat AND prevent the body from burning it...

In other words, the Alpha-2 receptor can hold your fat hostage & refuse to let go!

When it's activated, these areas can go into "lock-down" - storing fat like a bear preparing for hibernation...

Full-Fledged Thermogenesis

Luckily, this is where OxyELITE Pro™ shines...

By utilizing a compound that helps reduce the effectiveness the Alpha-2 receptor, we can use this to our advantage to torch fat quickly & efficiently when used in conjunction with a low-calorie diet and exercise program!*

Think of OxyELITE Pro™ as S.W.A.T - busting down doors and "freeing" your fat cells from their hostage situation...*

So sit back & strap on your seatbelt as this very well may be the most important info you've ever read on fat loss...

The OxyELITE Pro™ lineup...

Rauwolfia Canescens (Rauwolscine)

This particular compound has been suggested to block off & deactivate the Alpha-2 receptor!*

It's related to yohimbine, a compound which is often included in various thermogenic formulas because of its ability to antagonize alpha 2-adrenoceptors, allowing lipolysis itself, while also allowing lipolysis to continue from beta adrenoceptoragonism as well (11,12).*

Here's the problem: While antagonizing alpha 2-adrenoceptors is great, yohimbine unfortunately also does the same for alpha 1-adrenoceptors - and this may actually hinder lipolysis (13).*

So, on the other hand, while yohimbine may help improve lipolysis by antagonizing alpha 2-adrenoceptors, it may also prevent lipolysis from occurring by antagonizing alpha 1-adrenoceptors...*

Kind of defeats the purpose, huh? It's like robbing Peter to Pay Paul...

The end result may be only a mediocre or small effect upon fat loss, or no detectable fat loss at all, which is what has been suggested in some of the literature with yohimbine supplementation (14-17). *

Rauwolscine on the other hand, may be just as effective at antagonizing alpha 2-adrenoceptors as yohimbine, yet less potent at alpha 1-adrenoceptors (18), which may make it less likely to reduce lipolysis by inhibiting alpha 1-adrenoceptor activity when compared to yohimbine.*

Bauhinia purpurea L (Leaf & Pod [standardized for Bauhiniastatins 1-4])

This particular extract is very exciting because, due to various factors (e.g., stress, dieting, overtraining), many individuals may have impaired conversion of T4 to T3.*

We all know the thyroid plays an important role in metabolic rate.

An extract from the plant Bauhinia purpurea has been suggested in healthy adult animal models to increase T4 while also increasing T3 by an amazing 83%!* (21)

Yet another reason that increasing thyroid hormone is so important is because it's been surmised to sensitize or increase the lipolytic effects of adrenergic stimulation in fat cells* (33).

Due to the results of the studies, the authors concluded that the plant is likely increasing the conversion of peripheral T4 to T3.

Bacopa monnieri (Leaf)

This plant has also been suggested in an animal model to naturally promote thyroid hormone production.* In this case, the plant extract was suggested to increase T4 levels when compared to controls* (23).

In this case, however, since there was no increase in T3 seen, the authors concluded that the plant extract can directly stimulate the release of T4 from the thyroid gland, as opposed to Bauhinia purpurea, which increased the conversion of T4 to T3.

Geranium [Stems](extracted for 1,3-Dimethylamylamine)

Geranium has been used for centuries as a food additive and part of certain cultures' regular diets.

Cirsium Oligophyllum (Whole Plant Extract)

Our use of this plant is based upon an animal study which had suggested that compared to a control group, the extract studied was able to reduce the gain of bodyweight and fat mass and specifically seemed to target subcutaneous fat mass in rats over that of visceral fat mass!* (5)

Pharmacological studies suggest that the active constituent possesses beta adrenoceptor agonist activity and may stimulate lipolysis in subcutaneous fat cells.*

Yet another similarity that the Cirsiumoligophyllum extract shares with beta adrenoceptor agonists is that it can work synergistically with caffeine, potentially producing a more powerful lipolytic effect (5).*

In fact, the potency of caffeine & Cirsium Oligophyllum combined was nearly 10 times greater than Cirsium Oligophyllum by itself in this study.

Caffeine

Caffeine is often noted for its ability to increase resting energy expenditure, while also increasing lipolysis and lipid oxidation (6-8)...*

In addition, it is noted for its ability to increase feelings of energy, alertness, concentration and euphoric effects (9,10).*

Everyone throws caffeine in their formula...but few know why...we have a specific purpose on why we included it...

...Aside from the benefits that caffeine alone imparts, it may also provide synergistic effects when combined with other ingredients in OxyELITE Pro™...*

...In fact, in the study performed with Cirsiumoligophyllum, they surmised exactly that!*

Caffeine was suggested to provide an increase in the effectiveness of the extract at promoting lipolysis in subcutaneous fat cells (5)...*

Is Your Fat Burner Targeting The Wrong Fat?

Notice that we said subcutaneous fat cells as this is where many companies fail to make a distinction when creating thermogenics...

Many compounds can produce a decrease in fat mass when it comes to visceral fat (i.e., the fat that surrounds your organs), but when it comes to improving how you look, subcutaneous fat is what you're concerned with as this is the fat that is just below your skin and smothers up your muscles...

How Much Subcutaneous Fat You Have Means The Difference Between Looking Shredded Or Looking Like You Own Stock In A Donut House.

Most crappy high-stim thermogenics these days target visceral fat, not subcutaneous fat.

You need to get rid of excess subcutaneous fat to make a lean physique a reality.

The Final Frontier - The Incredible Fat Loss Pathway Science Had All But Given Up On

Consider this the icing on the cake...the 10th Ring for Phil Jackson...the next Billion Bill Gates makes...

Brown Adipose Tissue (BAT)

So, I'm sure we've all heard of this before, right?

It's often referred to as BAT, or simply as brown fat. It's very metabolically active and uses fat as fuel in order to produce heat. Pretty cool stuff, right?

Unfortunately, we were under the assumption we really only have significant amounts of brown fat when we're babies...

So, that's the end of the story, right? Well, very recently, the answer has become a solid, but surprising, no.

As it turns out, we fell into that trap often referred to as dogmatic thinking. If we're told something enough times and no one challenges it, we believe it...

Very recently, scientific studies have begun to call into question the notion adult humans lack BAT and that it has no potential to play any significant physiological role (24-29).

So, without any more procrastination, let's delve into the most recent findings:

• A recent study suggested that up to 96% of subjects evaluated have detectable levels of BAT! (24,25).
• It has been suggested that those who are overweight have lower BAT activity than those that are lean, something that isn't entirely a coincidence as having more BAT can potentially mean expending more calories and thus maintaining a lower weight (25).
• It has been estimated that more than half of all men and women likely have at least 10 grams of BAT in their body (26).
• BAT is so metabolically active that as little as 50 grams of BAT could potentially account for additional daily energy expenditure of an adult human when maximally stimulated (25,26).

Imagine how much of a difference that can make on how you look...

Ok, How Do We Recruit BAT?

The problem however is recruiting BAT and activating what little we have in the first place...

While exposure to cold is one method, it isn't exactly feasible to expose yourself to cold every day of the week...

...And aside from that, it has been pointed out that various environmental changes for modern humans such as insulated buildings, clothing advances and heated transport systems have all reduced the need for thermogenesis via BAT and thus the amount of activated BAT has decreased as well...

But all hope is not lost...

The other method is via sympathetic stimulation or in other words, by using direct and indirect-acting sympathomimetics (25,28).

Where OxyELITE Pro™ Goes From All-Time Great to First Ballot Hall of Fame

First, it's important to understand how BAT provides such benefits...

Now, normal white adipose tissue or WAT (i.e., the stuff around your organs and smothering your muscles) is generally there to accept extra energy from calories ingested and accepts them for storage as triglycerides (fat).

We need this to insulate us from the cold and protect our internal organs. BAT, on the other hand doesn't store extra energy as it instead dissipates this extra energy in the form of heat.

As you can see on the left, Brown Fat is much more "active" & thus can create much greater heat production (i.e burning fat for energy) than White Fat.
How does it do this? A major factor is a protein called uncoupling protein-1 (UCP-1).

Protein Uncoupling

This protein is able to uncouple oxidative phosphorylation, allowing the energy from foodstuffs that we consume to be released as heat (burned) instead of stored as fat (25,28,29).

Have you ever had one of those very lean friends that always complains about being, "hot" all of the time, even when it's the dead of winter?

These are the same friends that seem to eat nothing but junk food, yet still manage to stay lean all the time!

Well, BAT and UCP-1 activity may, in fact, be part of the reason!

So, plants or compounds that up-regulate the expression of UCPs, such as this plant, may help with fat loss in this way.

How OxyELITE Pro™ Attacks BAT

First, Geranium extract has sympathomimetic properties & this makes it a candidate for increasing UCP-1 expression and recruiting or regaining BAT so that we may use it once again.*

Secondly, Cirsium oligophyllum has beta adrenoceptor agonist activity and, as would be expected, has actually been suggested to increase UCP-1 activity in BAT of an animal model (5).*

Third, caffeine has been suggested to increase norepinephrine.

This increased norepinephrine again contributes to increasing UCP-1 activity in BAT, unfortunately, it also ends up activating alpha 2-adrenoceptors...

...And by doing this, it actually inhibits some of the potential lipolytic and thermogenic activity of norepinephrine by inhibiting adenylyl cyclase (i.e., the enzyme which allows for cyclic adenosine monophosphate or cAMP formation and what ultimately leads to lipolysis) activity (25,28).*

This is where rauwolscine comes in to play as it is an alpha 2-adrenoceptor antagonist. It prevents this inhibition of adenylyl cyclase and thus may potentially lead to a further increase in cAMP, lipolysis and thermogenesis via UCP-1...*

Again, this is where rauwolscine differs from yohimbine...

You see, the alpha 1-adrenoceptor is also activated by norepinephrine and it also contributes to increased UCP-1 activity and subsequent thermogenesis (28,29,31,32).*

At least one partial mechanism for how the alpha 1-adrenoceptor exerts such an effect is by supporting the conversion of T4 to T3 within BAT, which in turn increases UCP-1 expression.*

...So, although yohimbine has some beneficial effect upon fat loss, it's this blocking of activity at the alpha 1-adrenoceptor that becomes its downfall. Rauwolscine is less potent at antagonizing the alpha 1-adrenoceptor and thus makes a much better agent to use for fat loss.*

Last, but certainly not least, we still have both of our plant extracts designed to increase the release of T4 (Bacopa monnieri) and support the conversion of T4 to T3 (Bauhinia purpurea).*

As we just mentioned, T3 plays a role in UCP-1 expression so if we can elevate levels further, it is beneficial for a number of reasons...

...Of course, the fact that T3 can up-regulate beta adrenoceptor expression while down-regulating alpha 2-adrenoceptor expression, all while inhibiting phosphodiesterase (i.e., an enzyme that breaks down cAMP) activity further adds to increase or potentiate the effectiveness of the other ingredients (33).*

Best,

Jacob Geissler - CEO

P.S. - To truly maximize the result of any supplement, you must combine with proper nutrition & exercise plans. Feel free to visit our forums for information.

P.P.S. - It's mandatory that athletes or anyone subject to testing check with their governing body before using this product. Read the entire label, including directions & any precautions & warnings.

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