Phenibut Info And Products
Improves Relaxation And Mental Function

What is it and where does it come from?

Phenibut is derived from the neurotransmitter GABA.¹ GABA is a neurotransmitter responsible for nerve signal transmission efficiency, and elevated GABA levels are necessary for sound sleep.

What does it do and what scientific studies give evidence to support this?

Phenibut (beta-phenyl-gamma-aminobutyric acid) has a long history of clinical use in Russia.

Learn more about the benefits of Phenibut on Clayton South's Health Facts.

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All persons can benefit from phenibut supplementation due to its ability to induce relaxation and improve mental function. Phenibut supplementation may be especially efficacious for athletes and people living hectic, stress filled lifestyles.

No symptoms of deficiency exist.

Strictly adhere to label recommendations.

Tolerance is a side effect of chronic administration. Tolerance is a phenomenon whereby the body either:

1. Down regulates the endogenous production of a substance in response to elevated levels arising from exogenous introductions.
   Or

2. Reduces the affinity of its receptor sites to a ligand of exogenous origin

For this reason phenibut is typically cycled. Meaning: users of this supplement use phenibut for a period of one to two weeks and then cease administration for an equal amount of time. This allows for maximum benefit and minimal down regulation.

The toxicity of phenibut is very low. No reports of overdose have been reported when used in moderation, and no reports of dependency have emerged in scientific literature.

Persons on MAOI inhibitors or epilepsy medications like tegretol or trileptal should consult with their psychiatrist / physician prior to supplementation with phenibut. Clinical research has demonstrated that phenibut can potentate or inhibit the function of some epilepsy medications.

REFERENCES

1. Pavlov J Biol Sci. 1986 Oct-Dec;21(4):129-40. On neurotransmitter mechanisms of reinforcement and internal inhibition. Shulgina GI.

2. Arch Immunol Ther Exp (Warsz). 1975;23(6):733-46. Pharmacological properties of gamma-animobutyric acid and it derivatives. IV. Aryl gaba derivatives and their respective lactams. Chojnacka-Wojcik E, Hano J, Sieroslawska J, Sypniewska M.

3. Lapin I. Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Rev. 2001 Winter;7(4):471-81.

4. Neurosci Behav Physiol. 2003 Mar;33(3):255-61. Neurochemical characteristics of the ventromedial hypothalamus in mediating the antiaversive effects of anxiolytics in different models of anxiety. Talalaenko AN, Pankrat'ev DV, Goncharenko NV.

5. Eksp Klin Farmakol. 2002 Sep-Oct;65(5):22-6. [Monoaminergic and aminoacidergic mechanisms of the posterior hypothalamus in realization of the antiaversive effects of anxiosedative and anxioselective agents in various anxiety models] [Article in Russian]. Talalaenko AN, Pankrat'ev DV, Goncharenko NV.

6. Ross Fiziol Zh Im I M Sechenova. 2001 Sep;87(9):1217-26. [Neurochemical characteristics of the ventromedial hypothalamus and anti-aversive effects of anxiolytic agents in various anxiety models] [Article in Russian]. Talalaenko AN, Pankrat'ev DV, Goncharenko NV.

7. Ukr Biokhim Zh. 1984 Nov-Dec;56(6):637-41. [Mg2+-ATPase activity of brain mitochondria fractions in chronic stress and its correction by psychotropic agents] [Article in Russian]. Kresiun VI.

8. Farmakol Toksikol. 1991 Sep-Oct;54(5):14-6. [The adequacy of a new method for assessing the vestibular protective effect of biologically active substances] [Article in Russian]. Karkishchenko NN, Dimitriadi NA.

Republished from Clayton South's Health Facts.

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Cognitive Nutrition Phenibut, 750mg/60 Capsules	60	750	$0.71	$31.99 [Order]
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PrimaForce Phenibut, 90 Capsules	90	250	$0.84	$18.99 [Order]
PrimaForce Phenibut Powder, 100 Grams	333	300	$0.40	$39.99 [Order]
SNS Phenibut XT, 90 Capsules	60	500	$0.80	$23.89 [Order]

Other Phenibut Products

Name - Link	Servings	Price Per Serving	Lowest Price
Dymatize Elite Oats 'N More, 7 Packets	7	$1.71	$11.98 [Choose Flavor]
EP2 MusclePump, 120 Liquid Capsules	24	$2.33	$55.99 [Order]
Millennium Sport Somnidren-GH, 120 Grams	20	$1.75	$34.99 [Choose Flavor]
MoodPak Relax, 10 Cap Moodpaks	5	$1.40	$6.99 [Order]
MRM Relax-All, 60 Capsules	15	$1.09	$16.29 [Order]
Muscle Pharm Bullet Proof, 412 Grams	22	$2.00	$43.99 [Choose Flavor]
Nimbus Nutrition Abyss, 120 Capsules	30	$1.10	$32.95 [Order]
Nutrition53 Sleep1, 60 Capsules	30	$0.83	$24.99 [Order]
Pure Life Eden, 120 Grams	60	$0.70	$41.99 [Order]
Pure Life U4EA, 45 Capsules	11.3	$2.12	$23.99 [Order]
Pure Life U4EA, 90 Capsules	22.5	$1.87	$41.99 [Order]
Red Dawn Sleep Walker, 24 Packets - Clearance 33% OFF!	24	$2.78	$66.67 [Order]
SNAC Vitalyze, 90 Capsules	30	$0.58	$17.49 [Order]
Sports One 44-Sleep, 60 Capsules	30	$0.63	$18.99 [Order]
Youth Addict Psychotropin, 120 Capsules	30	$1.00	$29.99 [Order]