Out of 10
Read 44 Reviews
Out of 10
Read 44 Reviews

X-Factor Advanced

Contains A Proprietary Blend Of Arachidonic Acid & Other Botanicals
Supports Increased Muscle Mass And Strength!*
Supported Goal: Build Muscle
Main Ingredient: Arachidonic Acid
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Product Overview




Is a second-generation arachidonic acid (ARA) supplement. An Omega-6 fatty acid, ARA supports gains in muscle size, strength, and power, as well as muscle preservation during fat loss.* Studies suggest this fatty acid is essential for muscle protein synthesis following exercise.* Furthermore, regular exercise may lower ARA levels in the muscles. This makes ARA one of the most important supplements for bodybuilders and athletes. X-FACTOR ADVANCED takes ARA to the next level, with a formula designed to support the overall effect of this anabolic fatty acid.*


The effectiveness of X-FACTOR™ has been demonstrated in placebo-controlled trials at the University of Tampa. Thirty weight-training male subjects (age 20.4 ± 2.1 years) with a minimum of 1 year of resistance training experience were given six capsules of X-Factor per day (1,500mg ARA) or placebo for eight weeks. Subjects taking X-Factor noticed significantly greater improvements on all muscle size and performance variables tested, including an 88% greater increase in muscle size (thickness) measures. They also added an average of 21 lbs. to their bench press, 89 lbs. on leg press, gained about 4 lbs. of lean body mass (LBM), and noticed a 5.5 times greater increase in muscle power compared to placebo!*

XFA — Increased Potency

X-Factor™ Advanced is designed to further support the anabolic effects of arachidonic acid. The first objective was to increase the cellular uptake and membrane stability of this fatty acid, so more is available for post-training anabolism. Second, ARA must be metabolized to active bio-chemicals before it can trigger growth. Reducing its metabolism by other enzymes allows more ARA to be utilized by the primary anabolic pathway.* By focusing on both methods of ARA intensification, X-Factor Advanced represents the very pinnacle of ARA supplementation!

X-Factor™ or X-Factor™ Advanced?

X-Factor™ Advanced is generally recommended as the more effective and versatile ARA supplement. However, if you have a history of taking daily fish oil supplements in moderate to high doses, you may want to try original X-Factor first. Evidence suggests that at low levels, fish oil can potentiate the effects of ARA; at high levels it may reduce its effect. Omega-3’s have been added to XFA to increase ARA potency, but might be unnecessary if your tissue levels are already high.*


Arachidonic acid supplementation enhances in vitro skeletal muscle cell growth via a COX-2-dependent pathway. Markworth JF, Cameron-Smith D.Am J Physiol Cell Physiol. 2013 Jan 1;304(1):C56-67.

Effects of physical exercise on phospholipid fatty acid composition.

in skeletal muscle. Agneta Andersson, Anders Sjödin, Roger Olsson and Bengt Vessby. Am J Physiol Endocrinol Metab 274:E432-E438, 1998.

Effects of Arachadonic Acid on Skeletal Muscle Mass, Strength, and Power. NSCA 2014 National Conference. July 9-12, 2014.

Effects of arachidonic acid supplementation on training adaptations in resistance-trained males. Roberts MD, Iosia M et al.J Int Soc Sports Nutr. 2007 Nov 28;4:21.

The relation between the omega-3 index and arachidonic acid is bell shaped: Synergistic at low EPA/DHA status and antagonistic at high EPA/DHA status. M.Luxwolda, R. Kuipers, et al. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 85 (2001) 171-178

Patent # 6,841,573. Sold under license by Cargill, Inc.

Ratings & Reviews

Out of 10
Molecular Nutrition
X-Factor Advanced Reviews
44 Total Ratings
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    7.0 | 7 Ratings
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100 Softgels $44.86
100 Servings | $0.45 Per Serving
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What's in Molecular Nutrition X-Factor Advanced

100 Softgels
Serving Size: 1 Softgel
Servings Per Container:100
Amount Per Serving % Daily Value
Vitamin E (as d-alpha tocopherol) 2.5 mg 25%
Vitamin C 25 mg 42%
Magnesium (as magnesium oxide) 100 mg 25%
Potassium (as potassium citrate) 65 mg 2%
Selenium (as selenium selenite) 7 mcg 10%
X-FACTOR™ ADVANCED Proprietary Anabolic Formula 825mg **
ARASYN™ 40% Arachidonic Acid Oil, Fish Oil Concentrate, Boswellia Serrata Resin 65%
** Daily Value not established
Mortierella Alpha Oil (source of Arachidonic Acid), Kosher Gelatin, Kosher Glycerin, Natural Caramel Color, Purified Water

Directions For X-Factor Advanced: Take up to 4 servings daily with meals. Take for 50 days, then wait 50 days before repeating. Do not exceed the recommended dosage.

Warnings: Do not take this product if you are pregnant or nursing, or have any history of diabetes, asthma, high blood pressure, high cholesterol, arthritis, heart disease, stroke, colitis, irritable bowel syndrome, cancer, prostate enlargement, gastrointestinal surgery, or any inflammatory disease. Consult with your physician before use if you are taking any medication(s), or suffer from any health condition.

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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