Your Complete 2016 Supplement Guide

Ever wondered which supplements are backed by the most research, or which ingredients are best for your goals? Check out our comprehensive supplement review guide!

With the supplement industry booming bigger than ever, it's becoming harder to tell what works and what's marketing fluff. Luckily for you, we science nerds did the grunt work so you don't have to. We reviewed common supplement ingredients, herbs, vitamins, and minerals, and dived into the research and evidence behind their claims.

We came up with a list of the top 75 ingredients based on their intended function, along with a rating for each. The intended function includes both science-based claims as well as claims on product labels. The rating scale is a quick and simple method for you to evaluate each supplement based on available scientific evidence and anecdotal claims. We've even provided you with the optimal timing for each ingredient.

Before making any changes to your current diet and supplement plan, make sure to consult with your physician. Please remember that these ingredients are not intended to diagnose, treat, cure, or prevent any disease. If you have any underlying health conditions, or are pregnant, please consult with your physician before taking any supplements. The information listed in this guide is intended for use in adults only.


Excellent: This supplement's intended function is well-supported by a significant amount of scientific evidence. It can benefit most individuals, and is safe for use.

Great: This supplement has somewhat inconclusive findings, meaning some studies report positive changes following its use, while others report no change. The anecdotal evidence is favorable, and although more research is needed, it is still considered safe for use.

Good: There is currently minimal research available to support this ingredient's claims in a healthy population; however, it may be beneficial for individuals who are deficient in the ingredient. Anecdotal evidence is weak, but it is still considered safe for general use.

Compiled by Krissy Kendall, PhD, CISSN and Ciaran Fairman, MS, CISSN

Supplements Intended To Build Muscle/Increase Strength/Recovery

Sort By:

Supplements Intended For Weight Loss, Energy, and Endurance

Sort By:

Supplements Intended To Improve Immune Function, Inflammation, and Joint Health

Sort By:

Supplements Intended To Improve Mental Function, Mood, and Sleep

Sort By:

Vitamins, Minerals, and Antioxidants

Sort By:

* These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.