The results from an animal study that compared the absorption of the two different forms, as well as a human study showing significant absorption of ubiquinol, together suggest that taking ubiquinol orally may offer improved bioavailability in individuals who have difficulty achieving high levels of this nutrient, such as aging adults or those concerned with nutrient absorption.4* Comparison studies of the two forms are now necessary in humans to confirm this idea, as well as determine the specific circumstances under which ubiquinol may be more beneficial.
- Mohr, D., V.W. Bowry, and R. Stocker, Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation. Biochim Biophys Acta, 1992. 1126(3): p. 247-54.
- Weber, C., et al., Effect of dietary coenzyme Q10 as an antioxidant in human plasma. Mol Aspects Med, 1994. 15 Suppl: p. s97-102.
- Okamoto, T., et al., Human serum ubiquinol-10 levels and relationship to serum lipids. Int J Vitam Nutr Res, 1989. 59(3): p. 288-92.
- Hosoe, K., et al., Study on safety and bioavailability of ubiquinol (Kaneka QH) after single and 4-week multiple oral administration to healthy volunteers. Regul Toxicol Pharmacol, 2007. 47(1): p. 19-28.
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What's in Doctor's Best Best Ubiquinol
Directions For Best Ubiquinol: Take one softgel daily with food, or as directed by a nutritionally informed physician.
Warnings: Not suitable for vegetarians