ThermoLife T-Bol

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Lifting the unliftable. This is androbolic pull: Attracting the things you want. Drawing you closer to your goals. Igniting a towering androgen inferno inside of you with testosterone on top. A metabolism more intensely anabolic than any muscle-building challenge could possibly require. Catalyzing serial physique transformations from big to bigger to massive to surreal.

From ThermoLife, the industry source of the highest end body-building nutracologicals, comes T-BOL™, a boldly aggressive testosterone up-regulating formula which elevates and sustains endogenous production of testosterone and related androgens. Luxuriously pure and concentrated, it handles even the most brutal training regimes. Ideal for hardgainers and overtrainers. Makes you twice the athlete you used to be. Driven by eight pharmacologically active nutrients (nutracologicals) including Tribulus alatus (patent pending testosterone up-regulator), resveratrol (cardio protective anti-estrogen) and Urtica dioica (increases free testosterone). Thousands of satisfied customers and industry insiders around the world know T-BOL™ represents the highest end of endogenous testosterone up-regulating formulas. Get T-BOL™ today and give yourself the "androbolic pull" you need to build your best body ever.

T- BOL™ the exciting new natural testosterone augmenter and sexual performance enhancer has finally arrived.

T-BOL Maximum Strength Testosterone Enhancement Formula is the most comprehensive and powerful natural testosterone boosting formula ever developed. T-BOL works synergistically with your body's own endocrine system to naturally increase testosterone levels. Featuring a brand new STB (super testosterone booster) that raised testosterone levels in clinical studies more than any natural testosterone booster ever sold. This remarkable ingredient is combined with the most effective natural ingredients known to man for increasing the body's capacity to produce more of its own testosterone.

T-BOL works by stimulating the testosterone production centers of your endocrine system to produce more testosterone. In other words, T-BOL turns on the switch that tells your body to make testosterone and keeps it on! In addition T-BOL also enables your body to use the extra testosterone more efficiently by freeing bound testosterone and increasing receptor sensitivity. T-BOL will restore and BOOST your body's own testosterone production way beyond what your body can produce on its own (without T-BOL). As long as you supplement with T-BOL your body will pump out more testosterone into your blood stream where it can help to burn fat, fuel intense workouts, grow new muscle, gain strength, T-BOL can also be used as PCT (post cycle therapy). Continue reading on the following pages for ingredients and complete reference information.

*All ingredients present in pharmacologically significant amounts for pharmacological effects. A Trademark distinction of ThermoLife formulas.

Here are the ingredients we used and why:

Tribulus Alatus
Tribulus Terrestris was used successfully for years in many successful test-boosting products such as Tribosten and ThermoLife was proud to be the first company to isolate the active protodioscin from Tribulus Terrestris and develop a standard for it. However progress moves on and better compounds are always found. So we are proud to introduce to the world the successor of Tribulus Terrestris, Tribulus Alatus, exclusive and patent pending to ThermoLife International. A plant with many beneficial properties, such as hypoglycemic and hypolipidemic(1) , Tribulus Alatus is not only rich in Saponins found also in Tribulus Terrestris but also contains six novel steroidal saponins which S.A.R. research suggests them to be much, much more potent than those found in Tribulus Terrestris(2).

Eurycoma Longifolia (Longjack)
Eurycoma Longifolia is the scientific name of the Malaysian plant Tongkat Ali, also known as Longjack. In Malaysia it is identified as a symbol of a man's ego and strength, as it is used to increase male virility and sexual progress (7). Some of it's other beneficial actions are antiproliferative, antimalarian, antiviral, antihypertensive, antioxidant and anxiolytic (9,10,11,12,13,17). According to his published research studies based on human subjects (43,44,45), Tongkat Ali increased testosterone production in vitro and increased energy and feeling of well being, inhibited SHBG, increased ATP production in muscles and increased lean muscle mass. Despite its outstanding male sexual performance enhancing properties, until now Eurycoma has never made it as a great ingredient in test boosters. That was due to mainly two factors: First, the amount of actives present in all of today's Longjack containing supplements are severely under dosed most of the cheap extracts used are not standardized for the actual actives but standardized for cytotoxic compounds like eurycomanones. ThermoLife uses extract made by prime researchers on Longjack, standardized for concentration of the actual actives with minimum concentration on cytotoxic compounds.

Resveratrol
Resveratrol (3,5,4'-trihydroxystilbene) is a phytoalexin mainly found in red wine. To date it has found many uses due to its many benefits to human health. Such positive effects include strong antioxidant activity, antilipidemic, cardioprotective, antiproliferative, and antiatheroscleretic effects (26,27,28). One great property of this wonderful compound, which has never been put to use up until now is its ability to enhance male potency, sexual health, and strength (when administered in high enough amounts). Overall resveratrol was able to not only increase testosterone. The suggested mechanisms of action are its antiestrogenic effects, as resveratrol is an aromatase inhibitor and also has the capability to antagonistically bind to estrogen receptors. It also has strong antioxidant activities which can counter oxidant stress in the seminiferous tubules, thus protecting the testicle cells (29). Another beneficial action it has is anti-aromatase action both on enzyme and m-RNA levels (32).

Urtica Dioica
Urtica dioica, commonly known as stinging nettle, is a plant that grows aplenty in many Mediterranean countries like Greece and Turkey. It has a long history of use in traditional medicine, as well as being used for food. Examples of it's many beneficial properties are as an analgesic (33), antihyperglycemic (34), antioxidant (35) antiviral (36), Hepatoprotective (37), antihyperlipidemic (38), and an antithrombotic (39) agent. Of interest to bodybuilders is the capacity of certain Urtica Dioica lignans to bind with human sex hormone binding globulin (SHBG) (40,41,42). This effect results in the release of testosterone from SHBG, which makes it much more available for interaction with cells in order for it to exert its beneficial effects. Although we can't claim novelty with this compound since it's already available in quite a few successful products, ThermoLife is proud to continue with it's top quality standards by using a powerful 97% extract.

Forskolin
Forskolin is a labdane diterpene that is produced by the Indian Coleus plant (Plectranthus barbatus). Forskolin has a favorable effect on enhancing serum testosterone levels through it's potential influence on cAMP. Because LH exerts its effects on Leydig cells of the testicles (stimulating production of testosterone) through cAMP, an increase in testosterone levels using this compound is exhibited as well(43,44). In fact Forskolin is commonly used in studies to stimulate testosterone production from Leydig cells (45,46). Apart from this Forskolin exhibits a beneficial effect on reducing fat levels while increasing lean muscle mass.

Zinc
Zinc was added to the matrix because it's a mineral that is necessary for the body to create testosterone. Many males intake a lower amount of Zinc than is optimal for testosterone production, therefore preventing their body's from performing at their natural optimal testosterone producing capabilities. This means that the rest of T-BOL's stellar ingredients wouldn't be able to give the maximum results in such zinc deficient men, and to counter this 10mg of Zinc in a most bioavailable form (Glycine chelate) was added.

Lecithin
All steroidal compounds, like the steroidal saponins found in T Alatus need to be dissoluted in bile to be absorbed by the intestines. The presence of even small amountsof lecithin can increase the dissolution rates up to tenfold (47).

Bioperine
Bioperine is a patented piperine extract. Piperine has the capability of blocking glucuronidation(48), a main metabolic pathway that both lowers intestinal absorption and increases excretion, thus lowering the efficacy of many compounds present in T-BOL.

In Conclusion
T-BOL is specifically made to hit all possible aspects of androgen-enhancement, using what we consider to be the absolute best, top quality ingredients in effective doses. We left out what we considered to be ineffective, unneeded, or not worth the price.

To sum everything up so far, the compounds in T-BOL offer benefits such as:

1. Powerful ingredients each independently proven to increase androgen levels in T-BOL's dosages.
2. A highly bioavailable form of Zinc, more bioavailable than the one used in ZMA.
3. ncreases in testosterone releasing hormones LH and FSH.
4. Increases concentration of other anabolic hormones in the body by increasing concentration and providing precursors.
5. Protection from free radical damage.
6. Mild aromatase inhibition.
7. SHBG production inhibition.
8. Release of testosterone from SHBG.
9. Increases intramuscular ATP levels.
10. Increase energy and mood.
11. Inhibition of testosterone breakdown.

References

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2 Free serum testosterone level in male rats treated with Tribulus alatus extracts. El-Tantawy WH, Temraz A, El-Gindi OD.Drug Bioavailability Center, National Organization For Drug Control and Research, Cairo, Egypt. wldhmdy@yahoo.com
3 Phytochemistry. 2006 May;67(10):1011-8. Epub 2006 May 2 Steroidal saponins from the aerial parts of Tribulus alatus Del. Temraz A, El Gindi OD, Kadry HA, De Tommasi N, Braca A. Dipartimento di Chimica Bioorganica e Biofarmacia, Università di Pisa, Via Bonanno 33, 56126 Pisa, Italy.
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29. Wang Y, et al. “The red wine polyphenol resveratrol displays bilevel inhibition on aromatase in breast cells.” Toxicol Sci. 92(1), (Jul 2006): Pages 71-7.
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31. Bnouham M, et al. “Antihyperglycemic activity of the aqueous extract of Urtica dioica.” Fitoterapia. 74(7-8), (Dec 2003): Pages 677-81.
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33. Uncini Manganelli RE, et al. “Antiviral activity in vitro of Urtica dioica L., Parietaria diffusa M. et K. and Sambucus nigra L.” J Ethnopharmacol. 98(3), (Apr 2005): Pages 323-7.
34. Kanter M, et al. “Hepatoprotective effects of Nigella sativa L and Urtica dioica L on lipid peroxidation, antioxidant enzyme systems and liver enzymes in carbon tetrachloridetreated rats.” World J Gastroenterol. 11(42), (Nov 2005): Pages 6684-8.
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38. Schottner M, et al. “Lignans from the roots of Urtica dioica and their metabolites bind to human sex hormone binding globulin (SHBG).” Planta Med. 63(6), (Dec 1997): Pages 529-32.
39. Hryb DJ, “The effect of extracts of the roots of the stinging nettle (Urtica dioica) on the interaction of SHBG with its receptor on human prostatic membranes.” Planta Med. 61(1), (Feb 1995): Pages 31-2.
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45. Serotonin secretion from rat Leydig cells.Tinajero JC, Fabbri A, Ciocca DR, Dufau ML.Section on Molecular Endocrinology, National Institute of Child Health and Human Development, National Institute of Health, Bethesda, MD 20892.
46. Expression of testicular 3 beta-hydroxysteroid dehydrogenase/delta 5----4-isomerase: regulation by luteinizing hormone and forskolin in Leydig cells of adult rats. Keeney DS, Mason JI. Cecil H. and Ida Green Center for Reproductive Biology Sciences, Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas 75235-9051.
47. Dissolution of steroids in bile salt solutions is modified by the presence of lecithinAuteur(s) / Author(s) NAYLOR L. J. (1) ; BAKATSELOU V. ; RODRIGUEZ-HORNEDO N. ; WEINER N. D. ; DRESSMAN J. B. ; Affiliation(s) du ou des auteurs / Author(s) Affiliation(s) Abbott Laboratories, North Chicago IL, ETATS-UNIS
48. J Pharmacol Exp Ther. 1986 Feb;236(2):488-93. Piperine-mediated inhibition of glucuronidation activity in isolated epithelial cells of the guinea-pig small intestine: evidence that piperine lowers the endogeneous UDP-glucuronic acid content.
49. Body Composition and Hormonal Adaptations Associated with Forskolin Consumption in Overweight and Obese Men. Michael P. Godard, Brad A. Johnson and Scott R. Richmond. Obesity Research (2005) 13, 1335��"1343; doi: 10.1038/oby.2005.162