Obtaining adequate sleep is essential for maintaining mental alertness, physical performance, and positive mood. Occasional trouble sleeping can be related to environmental factors, such as light, jet lag, or shift-work.
Under normal conditions, the impulse to initiate sleep is driven by the body's internal clock mechanism. A brain structure known as the suprachiasmatic nucleus (SCN) responds to light and dark signals from the retina to influence body temperature and dictate the release of sleep promoting hormones. During dim or dark conditions, the SCN send signals to the pineal gland to trigger the release of melatonin, causing an increased desire to sleep. Artificial light, especially high frequency blue light from visual electronics, has been known to shift the release of melatonin and perturb sleeping patterns. Other physiological factors, such as mild stress, can diminish the ability to gain restful sleep.
The sleep inducing neurotransmitter, melatonin, also occurs naturally in many foods and can be taken as dietary supplement to help the body improve sleep patterns. Melatonin supplements have been suggested to be effective in certain groups of individuals who experience occasional sleep disturbances or are subjected to episodic sleep caused by jet-lag or shift work.* A recent study with subjects whose sleep cycle was offset showed improvements in sleep efficiency when taking melatonin thirty minutes prior to bedtime. A busy lifestyle can be detrimental to gaining restful sleep and can exacerbate existing problems. These compounds may ease the transition into sleep.* Lemon balm (Melissa officinalis) leaf extract has traditionally been used to support healthy sleep patterns .*
Combining melatonin and lemon balm leaf extract in a chewable tablet allows for quick absorption to help support relaxation and healthy sleep.* For best results, consume thirty minutes to one hour prior to bedtime. In addition, adequate rest is best established through a reliable sleep schedule, nutritious diet, and frequent exercise. The Melatonin 5 Pepperming Chewable w/ Lemon Balm can help set a sleep schedule and reduce the factors that interrupt healthy sleeping patterns. For healthiest results cycle off of using any melatonin product for 2 out of every 8 weeks.
- Colrain, I.M., Sleep and the brain. Neuropsychology review, 2011. 21(1): p. 1-4.
- McIntyre, I.M., et al., Human melatonin suppression by light is intensity dependent. Journal of pineal research, 1989. 6(2): p. 149-56.
- Buscemi, N., et al., The efficacy and safety of exogenous melatonin. A meta-analysis. Journal of general internal medicine, 2005. 20(12): p. 1151-8.
- Wyatt, J.K., et al., Sleep-facilitating effect of exogenous melatonin in healthy young men and women is circadian-phase dependent. Sleep, 2006. 29(5): p. 609-18.
- Sarris, J., et al., Herbal supplements . European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2011. 21(12): p. 841-60.
- Cases, J., et al., Pilot trial of Melissa officinalis L. leaf extract in the treatment of volunteers . Mediterranean journal of nutrition and metabolism, 2011. 4(3): p. 211-218.
- Kennedy, D.O., et al., Modulation of mood and cognitive performance following acute administration of single doses of Melissa officinalis (Lemon balm) with human CNS nicotinic and muscarinic receptor-binding properties. Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology, 2003. 28(10): p. 1871-81.