Joint support is especially necessary for those individuals who subject themselves to a highly active lifestyle; most athletes and bodybuilders are constantly loading and unloading their bodies depending on their particular training regimens. Joint support combines glucosamine and other vital ingredients to help promote healthy connective tissue and cartilage.*
Glucosamine is an amino sugar essential for this construction of strong cartilage and connective tissues. It is the foundation of proteoglycans, the large protein molecules that behave like sponges to hold water and give connective tissues their elasticity effects, and other substances that form protective tissues. Glucosamine provides a buffering action that protects against the wear and tear of joints, and consequently, tendons, ligaments, bones, skin, nails, mucous membranes, and other various body tissues cannot form properly without it.* The body will normally produce sufficient amounts of glucosamine needed to generate connective tissues, however the rate at which the body utilizes glucosamine begins to steadily change with increased athletic activity, age, etc. This can lead to a reduction in the amount of proteoglycans and protective lubricating substances like synovial fluid that are essential for protection of the joints. Thus, greater amounts of glucosamine are required, but less is produced internally. Oral glucosamine has been suggested to be easily absorbed to help in the promotion of healthy connective tissues.*
Among glucosamine and other ingredients, Joint Support also combines MSM, methyl-sulfonyl-methane, which is a unique biological sulfur necessary for human functioning. Sulfur is an activator of thiamine, biotin, Vitamin C, and pantothenic acid and offers the chemical links that form collagen and keratin. Collagen cannot be formed in the body without the presence of sulfur, thus, joint repair cannot take place without sulfur. MSM has been suggested to support joint flexibility, promote circulation, and support a healthy inflammatory response.*
1. Brien S, et al. (2008). Systematic review of the nutritional supplements dimethyl sulfoxide (DMSO) and methylsulfonylmethane (MSM). Osteoarthritis and Cartilage. 16:1277e.
2. Stanley Jacob, R.M. Lawrence, M. Zucker (1999). The Miracle of MSM: The Natural Solution. New York: Penguin-Putnam.
3. Uitterlinden EJ, Jahr H, Koevoet JL et al. (2006). Glucosamine decreases expression of anabolic and catabolic genes. Osteoarthritis and Cartilage / OARS, Osteoarthritis Research Society 14 (3): 250–7.
4. Vangsness Jr, C.; Spiker, W.; Erickson, J (2009). A review of evidence-based medicine for glucosamine and chondroitin sulfate use. Arthroscopy 25 (1): 86–94.