Infinite Labs: Cyclo Dex

Infinite Labs® Cyclo Dex™ has been scientifically formulated to optimize and enhance the anabolic environment by supporting a healthy estrogen balance, which ultimately promotes increased levels of circulating testosterone.* Cyclo Dex™ acts by metabolizing active estrogens into inactive estrogen metabolites, blocking estrogen, and by helping eliminate excess estrogen from the body.* It integrates research-based, anti-estrogen ingredients that support the anabolic benefits of increased levels of testosterone.*

Anti-Aromatase/Estrogen Management

The estrogen-blocking matrix in Cyclo Dex™ contains ingredients such as Diindolymethane (DIM) to further enhance the effects of circulating testosterone in the body. DIM is suggested for its ability to support the conversion of active estrogens into inactive estrogen metabolites.* These metabolites essentially free up the testosterone molecule by separating them from the testosterone-binding proteins, such as sex hormone-binding globulin; this ultimately promotes the circulation of free testosterone.* Along with DIM, Chrysin is also included in this matrix for its suggested role in limiting aromatase activity - the conversion of testosterone into estrogen.* Zinc has a reputation for being closely interrelated with testosterone and has been suggested to safely promote testosterone levels throughout the body, while Calcium D-Glucarate works to stabilize abnormally high levels of estrogen.* These, in combination with the natural testosterone-boosting effects of Japanese Knotweed Root, minimize the presence of estrogen molecules in the body and ultimately promote the utilization of testosterone.*

References

1. Chang YC, Riby J, Chang GH, Peng BC, Firestone G, Bjeldanes LF. Cytostatic and antiestrogenic effects of 2-(indol-3-ylmethyl)-3,3'-diindolylmethane, a major in vivo product of dietary indole-3-carbinol. Biochem Pharmacol . 1999;58:825-34.
2. Dhawan K, Kumar S, Sharma A (2002). "Beneficial effects of chrysin and benzoflavone on virility in 2-year-old male rats". J Med Food 5 (1): 43-8.
3. Le HT, Schaldach CM, Firestone GL, Bjeldanes LF. Plant-derived 3,3'-diindolylmethane is a strong androgen antagonist. J Biol Chem . 2003;278:21136-45. Epub 2003 Mar 27.
van Meeuwen JA, Korthagen N, de Jong PC, Piersma AH, van den Berg M. (2007). "(Anti)estrogenic effects of phytochemicals on human primary mammary fibroblasts, MCF-7 cells and their co-culture". Toxicol Appl Pharmacol. 221 (3): 372-83.
4. Zoltaszek R, Hanausek M, Kilianska ZM & Walaszek Z (2008). The biological role of D-glucaric acid and its derivatives: Potential use in medicine. Postepy Hig Med Dosw. 5(62): 451-62.