WHEN IS THE BEST TIME TO TAKE HMB

By Anonymous ( - 209.245.73.206) on Saturday, November 25, 2000 - 08:35 am: Edit

what brand of HMB did you buy anon ?

By Anonymous ( - 154.5.128.135) on Saturday, November 25, 2000 - 08:52 am: Edit

INTERACTIVE NUTRITION
HMB
THE SITE IS WWW.INTERACTIVENUTRITION.COM

By Anonymous ( - 209.245.73.206) on Saturday, November 25, 2000 - 08:59 am: Edit

are you arabic ?

By Anonymous ( - 154.5.129.196) on Saturday, November 25, 2000 - 09:08 am: Edit

AM I WHAT

By Anonymous ( - 209.245.73.206) on Saturday, November 25, 2000 - 09:11 am: Edit

HMB PART 1 AND 2

by David Greenwalt B.Sc.


In the January 1996 No. 47 issue of Muscle Media 2000 Bill Phillips
unleased a new supplement which he believes will be one of the best
supplements for bodybuilders on the market today. What is it?
Beta-hydroxy beta-methylbutyrate, (HMB). HMB is a leucine (one of the
branched chain amino acids) metabolite. Bill makes reference to a
study conducted at Iowa State University and the positive effects
observed by the persons conducting the study on healthy weight
lifters. The abstract of the study was presented at the June 2, 1995
conference for the American College of Sports Medicine in Minneapolis,
Minnesota. HMB is not new, however, the findings reported in the
abstract are. Let's take a look at it and decide for ourselves.

41 healthy males were randomly assigned to receive either 0, 1.5 or
3 grams of HMB per day in orange juice. Diets were meat-free for 3
days each week during which blood and urine were collected. The
abstract states that body composition was measured, however, it
doesn't state what the body comps were for each individual. The
subjects were weight-trained 3 times per week for three weeks. The
final numbers and conclusions of the abstract were that the group who
consumed 3 grams per day of HMB showed a 55% increase (over the
control) in lean tissue over the 3 week study. They conclude that HMB
appears to partially protect muscle damage and proteolysis (break down
of protein into amino acids) associated with strenuous muscle exercise
and in turn may lead to more rapid lean tissue gain.

The changes in lean mass were as follows for each group
respectively: The control ( 0 grams of HMB per day) group showed
a.4kg increase in lean mass, the 1.5g HMB group showed a .8kg increase
in lean mass and the 3g HMB group showed a 1.2kg increase on average.
There was also a measured strength increase which appeared to be dose
dependent, however, how they arrived at the increase is still unknown
to me so I won't print it here.

Sounds pretty impressive so far doesn't it? Finally, we have a
study with a control group using healthy weight lifters to determine,
not how much hair we can grow on the left index finger or whether our
skin will be silky smooth after use but to determine whether a
positive nitrogen balance could be obtained and to determine whether
body composition and strength changed in the healthy male
weight-lifter supplemented with HMB. It hits pretty close to home.

Some questions which come to mind don't dampen my spirits, but I do
feel they are legitimate. The abstract states the group started with
41 males. It doesn't say how many they finished with. It also
doesn't state whether the test subjects were screened for drug use
prior to the study and during the study. It's not necessarily normal
for healthy weight lifters to consume meat-free diets for three days a
week unless of course you're a vegetarian. These are potentially
small questions which may be explained by a more detailed description
of the study and how it was conducted but for now this is what we
have.

Bill Phillips also states in MM2K that a patent is owned by the
Iowa State University Research Foundation and has been licensed to
Metabolic Technologies Inc. regarding the nutritional use of HMB for
promoting nitrogen retention. This is true, however, he states that
if a product doesn't have the patent #5,348,979 on the bottle it's a
fake and don't buy it. What this infers to most readers is that this
patent protects the manufacture of HMB. It doesn't. What it does
protect is the nutritional uses of HMB for promoting nitrogen
retention and the explanation of those methods. You will see other
companies coming out with HMB. I'm not an attorney but a "Use" patent
is not the same as a "Manufacturing" patent. Other companies will be
coming out with HMB and it will be legitimate. One company, MET-Rx,
already has legitimate HMB in their High Performance Series MET-Rx
with HMB and others will follow in the months to come.

The abstract pertaining to the patent described above is rather
interesting and describes a positive nitrogen balance and the benefits
obtained therefrom. It states that "This invention relates to the
promotion of nitrogen retention in humans, and more particularly to
the administration of therapeutic agents for this purpose." So what?
Well read on...

Tissue proteins form the basis for organ structure and function.
Excessive losses of tissue protein can compromise organ function and
eventually will result in death. Any stressful situation such as
trauma and chronic debilitating diseases results in tissue losses that
if sustained can compromise organ function. In most cases nutrition
alone cannot prevent this tissue loss because of excessive breakdown
of tissue proteins. Thus, alternatives to nutrition must be used to
abate or slow the protein wasting or excessive loss of body nitrogen.

Nitrogen balance is the difference between the nitrogen intake (as
protein or amino acids) in an individual and the total nitrogen
excretion. When the nitrogen intake equals the nitrogen excretion,
the subject is in nitrogen equilibrium. If the nitrogen intake
exceeds the nitrogen excretion, the nitrogen balance is positive, but
if the nitrogen excretion is greater than the nitrogen intake, the
nitrogen balance is negative. Nitrogen balance can be estimated by
monitoring urinary nitrogen.

Promoting nitrogen retention has therapeutic importance where the
patient has been subjected to trauma or stress conditions which can be
expected to induce potential loss. Injury (surgical, traumatic, and
burn) result in accelerated protein breakdown, which is manifested by
increased nitrogen loss. Catabolic conditions are also frequently
associated with severe bodily diseases such as cancer, AIDS, etc. Loss
of muscle protein may occur due to normal aging, and consequently,
protein sparing therapy may be indicated for elderly patients who are
otherwise normal.

Further descriptions of the tested and proven benefits of HMB
administration for improved nitrogen retention and reduction of muscle
loss and wasting during stress and non stress situations are also
given. HMB appears, from the data we have at hand, to be orally
effective for promoting nitrogen retention. It is not known to be
toxic in doses up to 10 grams per 24 hour period or to have any
undesirable side effects. The preferable dosage is 2-6 grams per day
in divided amounts. It can be safely administered to persons
afflicted with trauma, stress or other catabolic conditions, including
people undergoing semi-starvation. HMB can also be used in
conjunction with weight loss programs where it is desired to minimize
loss of tissue protein. In general, the method of this invention can
be used to improve nitrogen balance for human subjects whenever it is
medically desirable to counter urinary nitrogen loss which cannot be
overcome nutritionally.

Wow! Was that a mouth-full or what? Isn't improved nitrogen
retention one of the reasons or the main reason we consume larger
quantities of protein powders and foods containing quality proteins?
Yes it is. Does HMB sound promising? Yes it does. Has anyone tried
it yet? Yes, I have. I've only been using it for 11 days as I write
this, however, and I feel it's too early to comment one way or another
at this time. I will keep you updated though. I expect I will know
whether it's going to work for me in another 2 weeks or so. It
doesn't mean that if it doesn't work for me that it won't work for
someone else. I've been burned in that arena too many times before.
We're all different and certain chemicals affect us all differently.
Until then, please let me know by writing, faxing or however you can
if HMB is working for you or what you've noticed anecdotally. It's
expensive right now. Hopefully the costs will come down in the near
future.

DID IT WORK OR DIDN'T IT?


Well, as you know from the last newsletter I tried HMB, the next
proposed miracle supplement from Bill Phillips of Muscle Media 2000.
As I stated in last months issue I wanted to give HMB a fair shake
before telling you all what I thought of it. After just under four
weeks of use I have to say that I wasn't impressed. On paper HMB
sounded great and we even have two studies now which allegedly show
the positive effects in body weight and strength for the study
participants. I, however, did not experience the same positive
results as those in the study. I can't say I experienced any results.
Bill Phillips states in his 1996 Supplement Review, a new book just
released by his organization, that he put on four pounds of lean mass
the first month and four pounds the second month. He rates HMB a
solid "A" for grade. It's possible it got rated a solid "A" because
he has an exclusive to sell HMB right now. Maybe it really did work
for him. Time will tell with HMB.

I know one thing for certain. After a few hundred of you try HMB,
whether it's from Phillips or from us after we get it in stock you'll
definitely let me know what you think of it and for that I am
grateful. Your empirical evidence is one of the truest measures of a
product's efficacy I know of. Studies can mount but if the masses
don't agree or feel the difference the studies don't mean squat.
Studies can also be manipulated. None of this is to say that the
studies associated with HMB thus far were poorly administered. It
just means that two positive studies don't balance my poor response.
Bioindividuality may be the limiting factor here and if that's the
case it will work for a good portion of you. There are those of you
who tell me creatine doesn't work for you. This is almost mind
boggling to me because it works so well for me and others but I
believe that it may not for a few. Vanadyl is another product that
works great for me but some of you stated you feel nothing. We're all
the same and at the same time we're all a different animal.

Since December 1995, when these articles were originally written,
a lot has happened with HMB and thousands of people have had the
chance to use HMB in capsule form. Basically, in a nutshell, HMB
capsules work for a placebo amount of about 30% of the people using
it. Placebo can account, easily, for up to 30% of any product's
success. HMB capsules fall into this category. HMB has been hyped,
torn apart, put back together and torn apart again in the bodybuilding
periodicals and it hasn't changed the fact that most users simply
don't notice the gains that Bill Phillips professed to us in the
latter part of 1995.

UPDATE JULY 1997

HMB: The Final Word

Twinlab finally paid enough money to uncle Bill to get their hands
on some HMB and so have released several new HMB-containing products.
HMB, short for beta-hydroxy-beta-methylbutyrate, was proclaimed to be
the next creatine monohydrate by Bill Phillips of Muscle Media back in
1995. In the present article writer Dennis Sparkman tells the story
of the infamous study that gave HMB all the unwarranted attention its
gotten for the past two years.

Big Bill proclaimed on the cover of his January 1996 issue of
Muscle Media 2000, "HMB: New Drug-Free Mass Builder! This Stuff Works
BIG TIME!". He also wrote on page 46 of the same issue "So you wanna
build more muscle size and strength... But you don't want to use
anabolic steroids (or you can't get em)...Whatta ya do? Don't give
up! Scientists have just discovered that a new, breakthrough
supplement called "HMB" may help make your "Bodybuilding Dreams" come
true!"

Prior to the January 1996 issue, however, many of you may not
remember that Bill wrote in the September 1995 issue this wonderful
quote, "Now, I'm about to tell you the most confidential information I
know, but mark my words.. by the year 2005 you'll be able to look back
at the late 1990s and see the incredible impact made on drug-free
muscle building by two agents knows as IPF and HMB. Remember you
heard it here first!!" IPF of course the compound never released
called Insulin Potentiating Factor.

Then, in the February 1996 issue of Muscle Media 2000 came the line
that killed Phillips' as even a remotely unbiased source of
information. In the middle of Dan Duchaine's Alternatives column, on
page 41, Dan wrote "A few months later, I received a query from Bill
Phillips asking if I would be interested in doing an article on HMB.
Scrawled across the page, handwritten, was the terse message: "Been
using it for three weeks, feels like Deca [Durabolin]." The "feels
like Deca" marketing bomb launched sales of HMB into the stratosphere
but the fallout has hurt Phillips seriously. Bill is rich, famous in
the small bodybuilding community and successful, but what he lost,
publishing the "Feels like Deca" comment was the trust and respect of
thousands of bodybuilders who bought the HMB and didn't think it felt
like Deca. As sneaky as it was, "Feels like Deca" has stayed with the
Muscle Media group like "I'll be back" has stayed with Arnold from the
successful Terminator movie.

As one of the first people to try HMB I started taking it in the
latter part of 1995. I took it as directed, 1 gram taken 3 times per
day. I initially reported about HMB in the December 1995 issue of
"Dave's Power Store News" and subsequently reported my results and the
results of some close and trusted friends in the January 1996 issue.
So about the time Bill was launching HMB sales skyward through
marketing hype, I alread knew the truth and reported it then.

Thousands have now had the opportunity to try HMB over the past two
years and we've listened to the comments of these buyers. Without a
doubt, HMB, in capsule form, is overwhelmingly a farce, ineffective,
and as close to placebo as I've seen I started The Power Store in
1992. I received zero benefits in muscularity, strength or fat loss
while taking HMB and over 70% of users, since I first took HMB, have
agreed wholeheartedly with my findings. While some 30% may report
favorably, placebo affects can easily account for the entire 30% of
the positive affects. In other words, the 30% could just as well be
taking a sugar pill and get the same "effects" they report from taking
HMB in capsule form. These poor souls are, in all likelihood,
probably one step away from becoming the next "Heaven's Gate"
disciples of recent illfated fame. Castrate yourself! O.K.. Take
poison, kill yourself, leave your friends and family behind, and let's
go for a ride on a spaceship! O.K.. Take HMB and you will grow big
time! O.K..

Now let's go back to where we started and talk about Twinlab's
release of their HMB versions. It's been almost two years since Bill
first uttered the HMB word and books and magazines have dissected HMB
to the best of their biased, flacid and impotent ability. Hell, Bill
even tricked the Associated Press into running a national press
release regarding HMB's purported effects at raising fat-free mass in
humans. Anyway, the study Twinlab is reporting on was published in a
1996 issue of the Journal of Applied Physiology.

The study enrolled 6 groups of young men, who obviously were very
untrained individuals with little experience in weight lifting,
regardless of what the study may report. Here's why. They exercised
10 times in three weeks. They would warm up and then do 3-5 sets of
90% of 1 rep max work. All groups, placebo and HMB supplemented, lost
weight. Huh? Why would intermediate or advanced lifters lose weight
from exercising 3 times per week? All groups got stronger during the
three week study. Huh? How much stronger can someone get in three
weeks when they're an intermediate or advanced lifter? In the end the
HMB supplemented group was reported to have gained more fat-free mass
and to be stronger than the placebo group. The researchers believe
it's related to a decrease in muscle tissue breakdown in the
HMB-supplemented group.

Now let's clear it up and finish this nightmare. Regardless of
what Dr. Nissen, the preeminent researcher for HMB says and regardless
of what protocol the study reports it's obvious that the individuals
enrolled in this study were newbies. Hell, they were greenhorns in
the first degree! If they weren't greenhorns they were typical gym
pussies who wouldn't know intensity if it bit them on the ear and tore
a chunk out like Tyson did to Holyfield recently. The test subjects
either fell into one of two categories: brand new lifter; jaw-flapping
wuss. Period. Why? Because intermediate and advanced lifters don't
lose weight working out 3 days per week unless calories are cut and
intermediate and advanced lifters don't get between 8% and 18.4%
stronger in 3 weeks unless they just started a steroid cycle or they
recently started creatine monohydrate supplementation. That's it!
Period. The only people who will lose weight by working out hard or
gain fat-free mass this quickly, by doing the same, are newbies!

Newbies, or a brand new lifter, will get stronger, possibly lose
weight and put on fat-free mass if they eat Ho Hos three times per
day. Newbies can do almost everything wrong and still blow away the
gains of an intermediate or advanced lifter. While the intermediate
or advanced lifter struggles to add 1 pound of lean mass per year, a
newbie can add 1 pound per month! Now, to keep things in perspective,
I need to add that an intermediate or advanced lifter may have added
between 25% and 40% to his original lean mass and may be a very large
or extremely muscular person by the time these gains come screeching
to a hault. So to clarify, I'm not saying a newbie looks better or is
stronger than an intermediate or advanced lifter, I'm simply saying
the initial newbie gains are biggest and they slow dramatically after
year number 2. In the beginning the muscle adapts and part of the
adaptation is growth of bigger and stronger muscle tissue. At some
point, after years of punishment, the muscle quits hypertrophying
(growing larger). The rate limiting factor (RLF) for why this occurs
is unknown, however there are few things we can do to overcome it.

Bill Phillips, Twinlab or any other company manufacturing HMB for
the lifter can stand on a stack of HMB studies for all I care. The
studies are flawed for the purposes of the lifter who needs it most-
the intermediate and advanced lifter. Telling us a newbie will gain
fat-free mass by taking a supplement is absolutely worthless. And I
mean worthless. It means nothing! They would gain regardless. HMB
can be shown to inhibit the release of 1000 different chemicals from
the muscle purported to indicate muscle protein breakdown and I could
care less. The muscle is supposed to release chemicals when we damage
it. It's supposed to get damaged so it can be repaired stronger. Our
body does a wonderful job of doing this until we reach our genetic
limit. When we reach this advanced level we can damage the hell out
of it but we don't appear to repair it stronger and bigger any more.
Sometimes, at this level, we damage it so much it gets severly injured
and tears from its insertion or origin. We really don't want to
reduce the damage, we just want the compensation of growing it bigger
and stronger to continue. Currently, at this advanced stage, the only
way to push your body to grow bigger muscle is by sticking a 22 guage
needle in your ass or you fine tune your diet and supplements as best
you can and hope for the best, slow but progressive gains. That's it!

HMB doesn't work any better in 1997 than it did in 1995. Twinlab
can come out with it and a thousand others can too. HMB, in
supplemental form, will not assist the intermediate or advanced lifter
gain lean mass or lose body fat.

What EAS has resorted to is mixing the HMB with creatine
monohydrate. Since creatine works so well and HMB sucks they figure
they can fool the buyer into thinking it must be the combination of
HMB and creatine that's giving them the results. Wrong! It's just
the creatine.

The only product I've seen, which contains HMB and has gotten
positive but still mixed reviews from users is MET-Rx with HMB. Last
year we took a survey which indicated that some 70% of users were very
happy with MET-Rx with HMB. I've used it and like it as well. Is
there truly a difference between the combination MET-Rx with HMB has
come up with and HMB in capsule form? I don't know. I responded
better to MET-Rx with HMB and others reported the same. This, in no
way, indicates it to be fact, however.

I'm not sure if I've made my self clear here so let me say
something one more time.

"HMB IN CAPSULE FORM SUCKS!"

(Sparkman, D., "HMB: Anticatabolic Supplement Increases Strength and
Muscle Mass", ANMD, August 1997:164)

Copyright 1997 by The Power Store, P.O.Box 33, Dixon, IL 61021. To
contact the author of this work or for additional copies please write
to The Power Store. References available upon request.

By Anonymous ( - 209.245.73.206) on Saturday, November 25, 2000 - 09:13 am: Edit

i made a good research just for you

you can learn everything about HMB

if you need anything let me know

By Anonymous ( - 154.5.129.196) on Saturday, November 25, 2000 - 09:15 am: Edit

THEN ALL YOU DO IS OPEN UP THE CAP AND PUT IN IN A CLASS WITH ORANGE JUICE. THEY ARE GEL CAPS THAT CAN BE OPENED

By Anonymous ( - 154.5.129.196) on Saturday, November 25, 2000 - 09:18 am: Edit

OH YAH WHAT DOES ARABIC MEAN

By Anonymous ( - 209.245.73.206) on Saturday, November 25, 2000 - 09:22 am: Edit

arabic means the people who live in the middle east :)

did you read the article ?

By Anonymous ( - 154.5.129.196) on Saturday, November 25, 2000 - 09:25 am: Edit

MAYBE

By Anonymous ( - 194.216.186.50) on Saturday, November 25, 2000 - 02:11 pm: Edit

haha this guy cracks me up!!!^^

By c. parke on Tuesday, December 05, 2000 - 07:10 pm: Edit

I have tried a lot of supplements- some work- some dont- I did not notice any change while taking HMB. I just dont feel that is is very effective.

By PerryJohnson on Friday, December 29, 2000 - 09:28 pm: Edit

Do you currently have Optimum Mega Potency HMB 1000mg/ 90 caps in stock?

By brian ( - 206.141.212.15) on Monday, January 01, 2001 - 05:22 pm: Edit

I've used EAS HMB and was taking 5 grams a day and didn't notice a thing! It looks good on paper but doesn't work in the real world!

By Tom25 on Tuesday, January 02, 2001 - 11:54 am: Edit

Oh really? I have a friend who did the Body For Life Challenge and said HMB worked wonders for him! He said his bodyweight didn't change but that he lost 4 or 5% bodyfat in 12 weeks!

By Akicita ( - 209.125.52.152) on Tuesday, January 02, 2001 - 10:50 pm: Edit

So? He could do that anyway, HMB had nothing to do with it; that's a perfectly reasonable result.

By freakish ( - 199.100.112.77) on Thursday, February 01, 2001 - 06:27 pm: Edit

I got off a cycle of 19nordiol and tribulus 4 weeks ago. To help reduce the loss from coming off this cycle, i have been taking 3 gram of HMB per day, and let me tell you, i have gotten stronger. I take it in the mronings, afternoon, and night, and i really do feel that my muscles are harder, and that i got stronger. I will continue to use it during my off-cycles, and when i cut down.
Kev.

By Anonymous ( - 209.245.69.225) on Friday, February 02, 2001 - 01:16 am: Edit

what bran did you use ?

By robertjay on Thursday, April 05, 2001 - 04:54 am: Edit

Should hmb be taken around the time you have meals or should you try and have it seperate?

By guruC (129.93.203.13) on Monday, May 07, 2001 - 08:42 am: Edit

I think most people feel that hmb doesn't work because they don't know how best to use it. The directions on the tubs are worthless and taking it 3 times a day as recommend by most brands will do nothing. Hmb's effects peak two hours after ingestion, so the thing to do is to take it about 90 mins prior to beginning your workout.. Remember it is a protein break down suppresser so it makes sense that it will work more effectivley if taken before the muscle are broken down from training. Also you need about 4g a day if under 200lb and 6g a day over 200lb. I have found that 3g before my workout, 2g after and 1g at night to be highly successfull at consitently increasing my strength over a period of time. I have recommended this dosing pattern to others and have found that they also started to experience good results. I hope this helps some of you out. (I have found that eas, metrx and twinlabs products are the best. Eas is the cheapest. I wouldn't trust the products from any of the other companies, remember hmb is very expensive so if they are selling it to cheap it has to be fake or padded down)

By Anubis (207.195.43.110) on Tuesday, May 15, 2001 - 09:17 am: Edit

I worked at a GNC for 3 years. Majority (90%)of all the people who tried HMB said that it did shit all for them. Plus there is so many articles out there that conclude that HMB is a waste of time and money

By joel (208.227.141.54) on Saturday, May 26, 2001 - 06:16 am: Edit

i bought a bottle and it did absoulely nothing for me except i had really rich urine....don't buy it. its expensive and it sucks!!!

By Dorian (12.90.104.212) on Saturday, May 26, 2001 - 09:55 pm: Edit

I have been trying to convey this for quite sometime but ...alas people beleive advertisements more.HMB is a waste of money and it is better to flush it as soon as you buy it cause that's where it is going to end up.
Dorian

By EHenryB (205.188.195.181) on Monday, May 28, 2001 - 08:29 am: Edit

I used HMB on a fat-loss cycle, and it worked great. It kind of reminds me of glutamine, but not as potent since it lacked the cell-hydration effect. I usually workout in the morning, weights and/or cardio, so I took 1 gram HMB and a thermogenic on an empty stomach beforehand. HMB acted as an anti-catabolic because I didn't feed my muscles upon awakening, and along with the thermogenic, help support the energy necessary for working out. Also, I took 3 more grams HMB throughout the day with protein or a MRP.

By Tony (63.24.180.57) on Sunday, July 29, 2001 - 01:23 pm: Edit

I got $200 worth of HMB for $6 at Vitamin World because it wasnt selling and they lowered it from $100 a bottle to $3 a bottle, but it was just that size bottle that wasnt selling, because it was so big and expensive, the small bottles stayed the same price
PS: it was EAS

By muscleup (205.188.196.29) on Monday, July 30, 2001 - 02:38 am: Edit

HMB AIDS IN YOUR RECOVERY. IT WORKS WELL WITH HYDROXYCUT AND RIPPED FUEL EXTREME. TWINLAB HAS THE BEST PRODUCTS AVAILABLE ON THE MARKET TODAY. I'VE BEEN USING THEM FOR YEARS. THEY HAVE AN HONEST VOICE IN SUPPLEMENTS.

By Adam (65.66.172.105) on Sunday, September 30, 2001 - 07:10 am: Edit

I've taken 3 grams daily of HMB continuously for the past 3 years. For me, it dramatically lessens the soreness that follows an intense workout.
On two occasions, I stopped using HMB for a week.
I found that the soreness was distracting enough to affect my workouts. This situation stopped, after a few days, once I started taking HMB again.