Pharmaceutical Name: GHB gamma hydroxy butyrate

Description: This compound is a naturally occurring metabolite of the amino acid GABA. Before it was removed from the over-the-counter market, supplement distributors purported GHB ability to increase natural growth hormone secretion. These claims were based on a 1977 study by the Third Department of Internal Medicine, Okayama University School of Medicine, Okayama Japan. In this study, it was discovered that GHB has a significant effect on pituitary hormones, specifically growth hormone (GH) and prolactin. In this trial, a dose of 2.5 grams of GHB was administered to a sample of healthy male subjects prior to sleep. What they observed were significant increases in plasma GH over a period of 90 minutes. These plasma GH levels reached peaks of nearly 40 mg/ml. This lead researchers to conclude that the supplementation of GHB stimulates the secretion of GH by the pituitary gland in healthy human subjects. GHB may cause a release in GH by modifying the amount of serotonin available from the nerve terminals. Others believe that GHB blocks the release of dopamine from nerve endings thus increasing the dopamine concentration of the brain. Others feels that a serotoninergic mechanism is responsible. GHB has been used for many years in parts of Europe and Japan for a variety of medical purposes. The therapeutic applications of this drug have been proven effective in the following areas: treatment of insomnia, anxiety, as an anesthetic, to relieve the withdrawal symptoms of alcoholics, to treat narcolepsy, to improve REM sleep, as a muscle relaxant, to treat tachycardia (rapid heartbeat), to treat sexual anxiety and inhibitions, and as a tranquilizer. This drug has a very wide mode of action. GHB is extremely popular with bodybuilders for a variety of reasons as web. Some feel the GH releasing effect contributes to anabolism and lipolysis. Other athletes use GHB to induce and improve the quality of sleep. This proven effect of GHB may aid in the recovery process. Other athletes use GHB as a diuretic. A number of athletes use GHB simply to tranquilize themselves. Often, a very euphoric sensation occurs after taking GHB which is attributable to an increase in brain dopamine levels. One expert has theorized that GHB exhibits its most beneficial effect on bodybuilders by reducing the body's endogenous cortisol levels. In this respect, GHB may be exhibiting its actions through an anti-catabolic mode.

Effective Dose: 1 teaspoon of the powder mixed with water before sleep.

Average Street Price: $20 per gram

Side Effects: GHB can cause extreme drowsiness. Large doses combined with central nervous system depressants including alcohol have caused some users to became extremely ill and required hospitalization. These cases of product misuse caused the FDA to remove GHB from the over-the-counter market.

By terry (152.163.194.189) on Sunday, September 30, 2001 - 08:09 am: Edit

Where can I find some GHB powder?